Research Associate II/Senior Research Associate, Preclinical Molecular Research

South San Francisco, California, United States
Full time

Encoded Therapeutics is a therapeutics company funded by world-class healthcare investors Venrock, Arch Venture Partners, Illumina Ventures, and Matrix Capital Management. At Encoded, we are combining the precision of gene regulation with the versatility of gene therapies to create breakthrough treatments for individuals living with severe genetic diseases.

We are recruiting a highly motivated research associate to join the Molecular and Cellular Pharmacology (MCP) team within the Preclinical Research department. The role will involve contributing to therapeutic design and validation, as well as performing preclinical studies for potential disease targets. A successful candidate will work collaboratively to support molecular and cellular-based assay design, execution and analysis in order to advance pipeline programs. They will demonstrate strong technical expertise in molecular biology and biochemistry, and will contribute to multiple projects in a fast-paced and dynamic research environment. For more information, please visit


  • Independently conduct and troubleshoot in vitro experiments and ex vivo assays in a Preclinical R&D environment with some guidance
  • Perform experiments in mammalian cell culturing with high proficiency
  • Demonstrate a high proficiency in molecular cloning and primer design
  • Demonstrate strong technical capabilities in MCP tasks including but not limited to: DNA/RNA/protein extraction from animal tissue and cultured cells, PCR, qPCR, cDNA library preparations, NGS sequencing, Western blotting, ELISA execution.
  • Analyze and interpret molecular, biochemical, and in vivo data with methodological rigor. Select and run appropriate statistical tests.
  • Participate in group meetings and present collated data packages for feedback and review
  • Follow company guidelines and document in detail experimental procedures, results and conclusions
  • Complying with all laboratory safety procedures
  • Perform additional tasks or assist with specialized projects as assigned or needed


  • Bachelors or Masters in biology or related field, with 5+ years experience to include pharmaceutical industry, preferably in a research environment
  • Strong hands-on technical skills related to molecular biology required
  • High proficiency in molecular cloning
  • Experience with mammalian cell culture and aseptic technique (primary cell culture
  • experience beneficial) required
  • Experience performing DNA, RNA, and protein-based assays
  • Some experience with viral vectors is preferred
  • Proficiency with molecular biology software such as Snapgene strongly preferred
  • Strong computer skills with a working knowledge of Microsoft Office suite, Graphpad Prism, or other data analysis software are required
  • Demonstrate good time management, organizational and prioritization skills, and attention to detail
  • Experience following protocols and maintaining detailed laboratory notebooks
  • Work effectively within team-focused environment to meet objectives under time constraints
  • Ability to independently formulate experimental plans based on overall project goals
  • Exhibit willingness and flexibility to meet project timelines
  • Excellent oral and written communication skills
  • Open to working collaboratively to meet tight timelines
  • Thrives in a dynamic and fast-paced research environment


  • Comprehensive benefits package, including competitive employer premium contributions
  • Meaningful stock option grants
  • PTO, sick time and holiday pay
  • Generous Parental Leave program
  • Pre-tax medical and dependent care programs
  • STD, LTD, Life and AD&D
  • Professional development opportunities
  • Team-building events
  • Fully stocked kitchen
  • Purple Tie dry cleaning service
  • Fitness center

Encoded is an Equal Opportunity Employer and prohibits discrimination and harassment of any kind. Encoded is committed to the principle of equal employment opportunity for all employees and to providing employees with a work environment free of discrimination and harassment. All employment decisions at Encoded are based on business needs, job requirements and individual qualifications, without regard to race, religion or belief, color, national origin, gender, status as a protected veteran, status as an individual with a disability, or any other status protected by the laws or regulations in the location in which we operate. Encoded will not tolerate discrimination or harassment based on any of these characteristics. Encoded encourages applicants of all ages.

If you need assistance or an accommodation due to a disability, you may call us at +1 650-491-0272.